Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647912 | 1.00 | CTDSP1 (0.35) | CTDSP1KCNH2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL10643136 | 0.91 | KCNH2 (0.40) | CTDSP1KCNH2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL10643131 | 0.91 | KCNH2 (0.40) | CTDSP1KCNH2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL9481609 | 0.90 | TDP1 (0.44) | CTDSP1TDP1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL9481600 | 0.90 | TDP1 (0.44) | CTDSP1TDP1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL10645127 | 0.89 | TDP1 (0.40) | CTDSP1KCNH2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL10645132 | 0.89 | TDP1 (0.40) | CTDSP1KCNH2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL10644255 | 0.89 | TDP1 (0.42) | KCNH2TDP1ALDH1A1HSD17B10MAPT | |
| SCHEMBL10644260 | 0.89 | TDP1 (0.42) | KCNH2TDP1ALDH1A1HSD17B10MAPT | |
| SCHEMBL10643411 | 0.87 | TDP1 (0.38) | CTDSP1KCNH2TDP1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057422-B1 | NEW CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-12 | — | — | EP | disclosed |
| EP-0191507-A2 | New 2-oxyimino-3-oxobutyric acid derivatives and process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |
| US-4452851-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-05 | — | — | US | disclosed |
| EP-0057422-A2 | New cephem compounds, processes for preparation thereof and pharmaceutical composition containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-08-11 | — | — | EP | disclosed |