Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 17/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10650514 | 0.90 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL10648259 | 0.85 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10650509 | 0.74 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL7316546 | 0.73 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7316932 | 0.71 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10672078 | 0.71 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10646411 | 0.71 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10672070 | 0.69 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10665392 | 0.69 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7314492 | 0.69 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254327-A2 | N-N-disubstituted-omega-(2-amino-3-(carbonylmethyl)-3,4-dihydroquinazolinyl) oxyalkylamides and related compounds | SYNTEX (U.S.A.) INC. (US) | 1988-01-27 | — | — | EP | disclosed |