Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647878 | 0.87 | FASN (0.44) | BCL2L1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10650903 | 0.84 | MEN1 (0.44) | ABCB1MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL11007640 | 0.83 | KMT2A (0.46) | BCL2L1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10649942 | 0.83 | SMN1; SMN2 (0.53) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10650734 | 0.80 | KDM4E (0.62) | MEN1KMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL10648440 | 0.78 | KMT2A (0.49) | BCL2L1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10650269 | 0.77 | MEN1 (0.51) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL10647925 | 0.76 | FASN (0.48) | MEN1KMT2AKDM4E | |
| SCHEMBL10651210 | 0.72 | PBRM1 (0.51) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL11007437 | 0.72 | KMT2A (0.71) | MEN1KMT2AALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0101330-B1 | 2-QUINOLONE DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4526894-A | Antiinflammatory agents | NIPPON SHINYAKU CO. LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0101330-A2 | 2-Quinolone derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1984-02-22 | — | — | EP | disclosed |