Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10648639 | 1.00 | OPRL1 (0.53) | OPRL1OPRM1OPRK1DPP4HRH3 | |
| SCHEMBL8278983 | 0.98 | OPRL1 (0.50) | OPRL1OPRM1OPRK1DPP4HRH3 | |
| SCHEMBL10992737 | 0.94 | OPRL1 (0.49) | OPRL1OPRM1OPRK1 | |
| SCHEMBL10992752 | 0.94 | OPRL1 (0.49) | OPRL1OPRM1OPRK1 | |
| SCHEMBL10992742 | 0.94 | OPRL1 (0.49) | OPRL1OPRM1OPRK1 | |
| SCHEMBL10644807 | 0.92 | OPRL1 (0.48) | OPRL1OPRM1OPRK1DPP4SLC18A3 | |
| SCHEMBL10645510 | 0.92 | OPRL1 (0.48) | OPRL1OPRM1OPRK1DPP4SLC18A3 | |
| SCHEMBL10645513 | 0.92 | OPRL1 (0.48) | OPRL1OPRM1OPRK1DPP4SLC18A3 | |
| SCHEMBL10644813 | 0.92 | OPRL1 (0.48) | OPRL1OPRM1OPRK1DPP4SLC18A3 | |
| SCHEMBL10647096 | 0.90 | OPRL1 (0.47) | OPRL1OPRM1OPRK1DPP4SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095626-B1 | PIPERIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1988-03-23 | — | — | EP | disclosed |
| US-4537698-A | DIELECTICS FOR ELECTROOPTICAL DISPLAY DEVICES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-08-27 | — | — | US | disclosed |
| EP-0095626-A2 | Piperidine derivatives | MERCK PATENT GmbH (DE) | 1983-12-07 | — | — | EP | disclosed |