Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456645 | 1.00 | TSHR (0.43) | TSHRALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL10658232 | 1.00 | TSHR (0.43) | TSHRALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL9363927 | 1.00 | TSHR (0.43) | TSHRALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL9325001 | 1.00 | TSHR (0.43) | TSHRALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL9332294 | 1.00 | TSHR (0.43) | TSHRALDH1A1EPHX1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9332700 | 0.99 | TSHR (0.44) | TSHRALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL10917287 | 0.99 | TSHR (0.42) | TSHRALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL10508458 | 0.99 | TSHR (0.42) | TSHRALDH1A1EPHX1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11011043 | 0.99 | TSHR (0.44) | TSHRALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL11202062 | 0.99 | TSHR (0.42) | TSHRALDH1A1EPHX1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115345-B1 | PROCESS FOR THE RESOLUTION OF RACEMIC OPTICALLY ACTIVE BICYCLIC IMINO-ALPHA-CARBOXYLIC ACID ESTERS AND USE OF THE COMPOUNDS OBTAINABLE IN THIS WAY FOR THE SYNTHESIS OF CARBOXYALKYL DIPEPTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-07 | — | — | EP | claimed |