Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8159333 | 0.88 | HDAC1 (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL8159419 | 0.86 | HDAC8 (0.51) | L3MBTL1TDP1HDAC3HDAC1HDAC2 | |
| SCHEMBL28444066 | 0.81 | KDM4E (0.55) | L3MBTL1CNR1HDAC3HDAC1HDAC2 | |
| SCHEMBL10652174 | 0.76 | HDAC1 (0.57) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL27760611 | 0.76 | KDM4E (0.42) | L3MBTL1TDP1GAASTSCNR1 | |
| SCHEMBL13254437 | 0.76 | HDAC3 (0.76) | CNR1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL3505506 | 0.76 | KMT2A (0.61) | GAA | |
| SCHEMBL9320350 | 0.76 | HDAC3 (0.76) | CNR1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL3504944 | 0.76 | KMT2A (0.61) | GAA | |
| SCHEMBL17252159 | 0.76 | HDAC3 (0.76) | CNR1HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161550-B1 | PROCESS FOR PRODUCING AN ALIPHATIC ISOCYANATE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-01-20 | — | — | EP | disclosed |