Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.61 |
| ▸ | SQLE | Q14534 | 7/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649679 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10567047 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11416886 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10567038 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL5312419 | 0.92 | KMT2A (0.48) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL1472220 | 0.92 | KMT2A (0.48) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL1472222 | 0.92 | KMT2A (0.48) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10669963 | 0.84 | SQLE (0.46) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10669969 | 0.84 | SQLE (0.46) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL1301692 | 0.81 | SQLE (0.73) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260551-A2 | Isoprene derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-03-23 | — | — | EP | disclosed |