Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 11/20 | 0.40 |
| ▸ | HTR2B | P41595 | 11/20 | 0.40 |
| ▸ | HTR2A | P28223 | 11/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649219 | 0.82 | HTR2C (0.37) | POLBHTR2CHTR2BHTR2AABCB1 | |
| SCHEMBL5474814 | 0.80 | POLB (0.41) | POLBABCB1MEN1KMT2ABRD4 | |
| SCHEMBL29920842 | 0.80 | POLB (0.47) | POLBABCB1BRD4CREBBP | |
| SCHEMBL29920576 | 0.80 | POLB (0.47) | POLBABCB1BRD4CREBBP | |
| SCHEMBL9818767 | 0.78 | AKR1B1 (0.45) | POLBABCB1MEN1KMT2A | |
| SCHEMBL10650423 | 0.78 | HTR2C (0.40) | POLBHTR2CHTR2BHTR2ASLC6A2 | |
| SCHEMBL9818765 | 0.78 | AKR1B1 (0.45) | POLBABCB1MEN1KMT2A | |
| SCHEMBL15825584 | 0.77 | SLC6A2 (0.42) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL1328841 | 0.77 | POLB (0.43) | POLBHTR2CHTR2BHTR2AABCB1 | |
| SCHEMBL18383190 | 0.77 | POLB (0.43) | POLBHTR2CHTR2BHTR2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157267-B1 | SUBSTITUTED BENZOPYRANS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1988-11-23 | — | — | EP | disclosed |
| US-4659737-A | Substituted aminomethyl benzopyrans having anti-hypertensive activities | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| EP-0114374-B1 | SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| US-4563458-A | CIRCULATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| EP-0157267-A2 | Substituted benzopyrans, process for their preparation and their use in medicines | BAYER AG (DE) | 1985-10-09 | — | — | EP | disclosed |
| EP-0114374-A1 | Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines | BAYER AG (DE) | 1984-08-01 | — | — | EP | disclosed |