Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 6/20 | 0.94 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.74 |
| ▸ | FNTA | P49354 | 11/20 | 0.59 |
| ▸ | FNTB | P49356 | 11/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126194 | 0.89 | GRIA4 (0.80) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL16792125 | 0.87 | GRIA4 (0.78) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3136013 | 0.87 | GRIA4 (0.77) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL10652831 | 0.86 | GRIA4 (0.71) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3125313 | 0.85 | GRIA4 (1.00) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL10656067 | 0.84 | GRIA4 (0.80) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3128700 | 0.84 | GRIA4 (0.73) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL2681861 | 0.83 | GRIA4 (0.67) | GRIA4GRIA2FNTAFNTBKDM4E | |
| SCHEMBL3135460 | 0.80 | GRIA4 (0.67) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3134093 | 0.79 | GRIA4 (0.65) | GRIA4GRIA2FNTAFNTBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |