Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656367 | 1.00 | RARB (0.52) | RARBSMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL10658006 | 1.00 | RARB (0.52) | RARBSMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL10658636 | 1.00 | RARB (0.52) | RARBSMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL10655588 | 1.00 | RARB (0.52) | RARBSMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL10656505 | 1.00 | RARB (0.52) | RARBSMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL10654132 | 1.00 | RARB (0.52) | RARBSMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL10656576 | 0.99 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL10657182 | 0.99 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL10658338 | 0.99 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL10660350 | 0.99 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257048-A1 | OPTICALLY ACTIVE COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-02 | — | — | EP | disclosed |
| WO-1987005018-A2 | OPTICALLY ACTIVE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-08-27 | — | — | WO | disclosed |