Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656864 | 0.93 | CHRM1 (0.34) | CHRM1EGFRKMOALDH1A1POLB | |
| SCHEMBL9781598 | 0.93 | CHRM1 (0.33) | CHRM1EGFRKMOPOLB | |
| SCHEMBL10374363 | 0.88 | CHRM1 (0.36) | CHRM1EGFRKMOALDH1A1POLB | |
| SCHEMBL38805 | 0.84 | CHRM1 (0.36) | CHRM1POLB | |
| SCHEMBL29577537 | 0.84 | CHRM1 (0.36) | CHRM1POLB | |
| SCHEMBL16063458 | 0.82 | EGFR (0.34) | CHRM1EGFRKMOALDH1A1POLB | |
| SCHEMBL6826971 | 0.81 | CHRM1 (0.36) | CHRM1POLB | |
| SCHEMBL10655155 | 0.81 | CHRM1 (0.36) | CHRM1EGFRKMOALDH1A1POLB | |
| SCHEMBL16063579 | 0.81 | EGFR (0.35) | CHRM1EGFRKMOALDH1A1MEN1 | |
| SCHEMBL15779803 | 0.81 | CHRM1 (0.37) | CHRM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0176101-B1 | TRIAZOLOPYRIDAZINES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-07-06 | — | — | EP | claimed |
| US-4619687-A | Triazolopyridazines and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-10-28 | — | — | US | claimed |
| EP-0176101-A1 | Triazolopyridazines, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-04-02 | — | — | EP | claimed |
| EP-0176101-B1 | TRIAZOLOPYRIDAZINES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-07-06 | — | — | EP | disclosed |
| US-4619687-A | Triazolopyridazines and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-10-28 | — | — | US | disclosed |
| EP-0176101-A1 | Triazolopyridazines, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-04-02 | — | — | EP | disclosed |