Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.58 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | PTGIR | P43119 | 2/20 | 0.51 |
| ▸ | CETP | P11597 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009650 | 0.84 | PTGDR2 (0.80) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1062594 | 0.80 | PTGDR2 (0.79) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1065384 | 0.80 | PTGDR2 (0.55) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1010101 | 0.79 | PTGDR2 (0.67) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2280515 | 0.77 | PTGDR2 (0.55) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL13521853 | 0.77 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2283553 | 0.76 | PTGDR2 (0.57) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2275833 | 0.76 | PTGDR2 (0.52) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1010330 | 0.76 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1008769 | 0.75 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268611-A2 | AMINOALKYLPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009145989-A2 | AMINOALKYLPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-12-03 | — | — | WO | disclosed |