Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 0.72 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.72 |
| ▸ | P2RY12 | Q9H244 | 15/20 | 0.60 |
| ▸ | PDE2A | O00408 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10657367 | 0.98 | PDE3B (0.69) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10760182 | 0.84 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10659738 | 0.79 | PDE3B (0.68) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10760128 | 0.79 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10654036 | 0.79 | PDE3B (0.75) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10758046 | 0.77 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| Hydrochloric Acid SCHEMBL10657366 | 0.77 | PDE3B (0.72) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10655655 | 0.75 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10656517 | 0.74 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10658552 | 0.74 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775674-A | CARDIOTONIC AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-10-04 | — | — | US | claimed |
| US-4775674-A | CARDIOTONIC AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-10-04 | — | — | US | disclosed |