Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651430 | 1.00 | AKR1B1 (0.46) | AKR1B1MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL10653318 | 0.84 | AKR1B1 (0.47) | AKR1B1MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL10650449 | 0.84 | AKR1B1 (0.47) | AKR1B1MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL10649392 | 0.82 | AKR1B1 (0.46) | AKR1B1MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL10647106 | 0.81 | AKR1B1 (0.50) | AKR1B1MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL10647195 | 0.81 | AKR1B1 (0.50) | AKR1B1MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL10883717 | 0.81 | AKR1B1 (0.50) | AKR1B1MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL10754485 | 0.73 | AKR1B1 (0.49) | AKR1B1MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL10651362 | 0.72 | AKR1B1 (0.37) | AKR1B1MAPTNPC1ALDH1A1TSHR | |
| SCHEMBL10755930 | 0.70 | SMN1; SMN2 (0.41) | MAPTNPC1ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173522-B1 | PROCESS AND INTERMEDIATES FOR SORBINIL | PFIZER INC. (US) | 1988-12-07 | — | — | EP | claimed |