Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657814 | 0.99 | ELANE (0.68) | ELANEMEN1KMT2AHCAR2 | |
| SCHEMBL2078231 | 0.99 | ELANE (0.68) | ELANEMEN1KMT2AHCAR2 | |
| SCHEMBL10662348 | 0.92 | ELANE (0.74) | ELANEMEN1KMT2A | |
| SCHEMBL10659004 | 0.86 | ELANE (0.62) | ELANEMEN1KMT2AHCAR2 | |
| SCHEMBL2077786 | 0.85 | ELANE (0.52) | ELANEMEN1KMT2A | |
| SCHEMBL2076871 | 0.84 | ELANE (0.74) | ELANEMEN1KMT2A | |
| SCHEMBL2077850 | 0.84 | ELANE (0.51) | ELANEMEN1KMT2A | |
| SCHEMBL2078781 | 0.84 | ELANE (0.51) | ELANEMEN1KMT2A | |
| SCHEMBL2075748 | 0.84 | ELANE (0.51) | ELANEMEN1KMT2A | |
| SCHEMBL2078449 | 0.83 | ELANE (0.72) | ELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |
| US-4665070-A | SERINE PROTEINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0206323-A1 | 2-Oxy-4H-3,1-benzoxazin-4-one derivatives and related compounds | SYNTEX (U.S.A.) INC. (US) | 1986-12-30 | — | — | EP | disclosed |