SCHEMBL1065498

SCHEMBL1065498

O=C(O)c1ccc(CS(=O)(=O)O)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
CASP1 P29466 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NR1H4 Q96RI1 1/20 0.45
PTPRC P08575 2/20 0.43
PTPRG P23470 2/20 0.43
MYC P01106 1/20 0.41
NR4A1 P22736 1/20 0.41
ALDH1A1 P00352 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
CISD1 Q9NZ45 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1061633 0.86 SLC22A12 (0.39) TSHRCASP1SMN1; SMN2NR1H4PTPRC
SCHEMBL1018464 0.85 TSHR (0.50) TSHRCASP1SMN1; SMN2NR1H4PTPRC
SCHEMBL9558139 0.80 TSHR (0.61) TSHRCASP1SMN1; SMN2NR1H4PTPRC
SCHEMBL11702627 0.80 IDO1 (0.48) TSHRKMT2AMEN1
Hydrochloric Acid SCHEMBL28306765 0.78 IDO1 (0.47) TSHRKMT2AMEN1
SCHEMBL2140516 0.78 TSHR (0.59) TSHRCASP1SMN1; SMN2NR1H4PTPRC
SCHEMBL543139 0.78 SMN1; SMN2 (0.59) TSHRCASP1SMN1; SMN2NR1H4PTPRC
SCHEMBL30463143 0.78 SMN1; SMN2 (0.59) TSHRCASP1SMN1; SMN2NR1H4PTPRC
SCHEMBL11701150 0.78 IDO1 (0.47) TSHRKMT2AMEN1
SCHEMBL9391004 0.78 IDO1 (0.47) TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2451778-A1 STABLE CRYSTALLINE POLYMORPH OF 2-(2-CHLORO-4-MESYL- BENZOYL)-CYCLOHEXANE/-1,3-DIONE AND PROCESS FOR PREPARING THE SAME Sapec-Agro, Sa (PT) 2012-05-16 EP disclosed
WO-2011005127-A1 STABLE CRYSTALLINE POLYMORPH OF 2-(2-CHLORO-4-MESYL- BENZOYL)-CYCLOHEXANE/-1,3-DIONE AND PROCESS FOR PREPARING THE SAME SAPEC-AGRO, SA (PT) 2011-01-13 WO disclosed