Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11781452 | 0.84 | HDAC1 (0.47) | HPGDNPSR1MCOLN3HDAC1HDAC6 | |
| SCHEMBL27002437 | 0.81 | NPSR1 (0.51) | HPGDNPSR1MCOLN3HDAC1HDAC6 | |
| SCHEMBL16905393 | 0.80 | HDAC1 (0.58) | HPGDHDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL16689552 | 0.77 | HDAC1 (0.58) | HDAC1HDAC6ALDH1A1LMNAKDM4E | |
| SCHEMBL30786345 | 0.76 | HPGD (0.66) | HPGDHDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL471664 | 0.76 | HPGD (0.66) | HPGDHDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL4102311 | 0.76 | NPSR1 (0.60) | HPGDNPSR1MCOLN3ALDH1A1LMNA | |
| SCHEMBL5776326 | 0.75 | HDAC1 (0.51) | HPGDHDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL22194152 | 0.75 | NPSR1 (0.44) | HPGDNPSR1MCOLN3HDAC1HDAC6 | |
| SCHEMBL30727808 | 0.75 | NPSR1 (0.44) | HPGDNPSR1MCOLN3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0133310-B1 | IMIDAZOLIDINONES, AND IMIDAZOLIDINETHIONES, PROCESS FOR THE PREPARATION THEREOF, AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4608079-A | Imidazolidinones, and imidazolidinethiones, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1986-08-26 | — | — | US | disclosed |
| US-4554013-A | Herbicidal imidazolinyl naphthoic acids | AMERICAN CYANAMID COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
| EP-0133311-A2 | Substituted imidazolinyl benzoic acids, esters and salts and use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |
| EP-0133310-A1 | Imidazolidinones, and imidazolidinethiones, process for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |