Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655943 | 0.83 | BLM (0.50) | BLMLMNACA1KDM4CKDM4A | |
| SCHEMBL10655950 | 0.83 | BLM (0.50) | BLMLMNACA1KDM4CKDM4A | |
| SCHEMBL27458546 | 0.78 | BLM (0.60) | BLMLMNACA1PTPN1KDM4C | |
| SCHEMBL28455451 | 0.78 | BLM (0.60) | BLMLMNACA1PTPN1KDM4C | |
| SCHEMBL28455377 | 0.76 | BLM (0.58) | BLMLMNAPTPN1KDM4CKDM4A | |
| SCHEMBL28337237 | 0.75 | BLM (0.47) | BLMLMNACA1PTPN1 | |
| SCHEMBL8542664 | 0.72 | — | — | |
| SCHEMBL9405652 | 0.72 | — | — | |
| SCHEMBL9405651 | 0.72 | — | — | |
| SCHEMBL4971007 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257048-A1 | OPTICALLY ACTIVE COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-02 | — | — | EP | disclosed |
| WO-1987005018-A2 | OPTICALLY ACTIVE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-08-27 | — | — | WO | disclosed |