SCHEMBL10656314

SCHEMBL10656314

CCCCCCCC(Br)C(=O)Cl

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.67
PPARD Q03181 1/20 0.67
ZDHHC20 Q5W0Z9 1/20 0.67
ZDHHC2 Q9UIJ5 1/20 0.67
ZDHHC7 Q9NXF8 2/20 0.60
GPR84 Q9NQS5 7/20 0.47
FFAR1 O14842 2/20 0.47
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
MAPT P10636 1/20 0.45
CA2 P00918 1/20 0.44
FAAH O00519 1/20 0.43
FFAR4 Q5NUL3 1/20 0.42
ACE2 Q9BYF1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5974589 1.00 LCK (0.67) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL844558 1.00 LCK (0.67) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL7949690 1.00 LCK (0.67) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL8451807 1.00 LCK (0.67) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL18300692 0.98 LCK (0.63) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL306336 0.91
SCHEMBL9583527 0.83 LCK (0.45) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL4968295 0.81
SCHEMBL23829555 0.80 LCK (1.00) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL2721068 0.80 LCK (1.00) LCKPPARDZDHHC20ZDHHC2ZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0152935-B1 PROCESS FOR PREPARING 2,2,6,6-TETRAMETHYL-4-OXOPIPERIDINE ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1988-11-30 EP disclosed
EP-0152934-B1 METHOD FOR PREPARING 2,2,6,6-TETRAMETHYL-4-OXOPIPERIDINE ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1988-09-14 EP disclosed
US-4663459-A FROM AMMONIA AND ACETONE WITH ACYLHALIDE CATALYST ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1987-05-05 US disclosed
US-4661597-A FROM ACETONE AND ACETONING WITH AN ORGANIC ACID HALIDE CATALYST ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1987-04-28 US disclosed
EP-0152935-A1 Process for preparing 2,2,6,6-tetramethyl-4-oxopiperidine ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1985-08-28 EP disclosed
EP-0152934-A1 Method for preparing 2,2,6,6-tetramethyl-4-oxopiperidine ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1985-08-28 EP disclosed
EP-0061899-B1 MORPHOLINES JOHN WYETH & BROTHER LIMITED (GB) 1985-03-20 EP disclosed
US-4387097-A Morpholines JOHN WYETH AND BROTHER LIMITED (GB) 1983-06-07 US disclosed