Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651607 | 0.87 | NQO1 (0.59) | NQO1TOP2ANPSR1MAPTKMT2A | |
| SCHEMBL10655030 | 0.87 | NQO1 (0.49) | NQO1TOP2ACYP3A4CYP2C9MAPT | |
| SCHEMBL10654692 | 0.86 | NQO1 (0.60) | NQO1TOP2ACYP3A4CYP2C9MAPT | |
| SCHEMBL10652380 | 0.82 | NQO1 (0.61) | NQO1TOP2ACYP3A4CYP2C9NPSR1 | |
| SCHEMBL10847461 | 0.80 | NQO1 (0.73) | NQO1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL10652384 | 0.74 | NQO1 (0.60) | NQO1TOP2AMAPTKMT2ANPC1 | |
| SCHEMBL10651593 | 0.74 | NQO1 (0.78) | NQO1TOP2ANPSR1KMT2AMEN1 | |
| SCHEMBL10649172 | 0.73 | NQO1 (0.69) | NQO1NPSR1MAPTKMT2AMEN1 | |
| SCHEMBL10650670 | 0.73 | NQO1 (0.77) | NQO1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL10850685 | 0.72 | NQO1 (0.90) | NQO1MAPTKMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138302-B1 | PYRAZOLO(3,4,5-KL)ACRIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-03-09 | — | — | EP | disclosed |
| US-4555572-A | Pyrazolo[3,4,5-kl]acridine compositions and methods for their production and use | WARNER-LAMBERT COMPANY (US) | 1985-11-26 | — | — | US | disclosed |
| EP-0138302-A1 | Pyrazolo(3,4,5-kl)acridine compounds, pharmaceutical compositions comprising the same and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |