Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656351 | 1.00 | MAPT (0.48) | MAPTMEN1KMT2AHPGDPOLB | |
| SCHEMBL10658215 | 0.95 | MAPT (0.47) | MAPTMEN1KMT2AHPGDPOLB | |
| SCHEMBL10658221 | 0.95 | MAPT (0.47) | MAPTMEN1KMT2AHPGDPOLB | |
| SCHEMBL10656339 | 0.85 | MAPT (0.49) | MAPTMEN1KMT2AHPGDPOLB | |
| SCHEMBL10656336 | 0.85 | MAPT (0.49) | MAPTMEN1KMT2AHPGDPOLB | |
| SCHEMBL10656100 | 0.84 | HPGD (0.45) | MAPTMEN1KMT2AHPGDPOLB | |
| SCHEMBL10656094 | 0.84 | HPGD (0.45) | MAPTMEN1KMT2AHPGDPOLB | |
| SCHEMBL10655606 | 0.84 | MAPT (0.49) | MAPTMEN1KMT2AHPGDPOLB | |
| SCHEMBL10655609 | 0.84 | MAPT (0.49) | MAPTMEN1KMT2AHPGDPOLB | |
| SCHEMBL10757993 | 0.84 | MAPT (0.56) | MAPTMEN1KMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775674-A | CARDIOTONIC AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-10-04 | — | — | US | disclosed |