Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656364 | 1.00 | PTPN1 (0.45) | PTPN1PDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL10657585 | 0.97 | PTPN1 (0.46) | PTPN1PDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL10657595 | 0.97 | PTPN1 (0.46) | PTPN1PDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL10661186 | 0.89 | HPGD (0.41) | PTPN1PDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL10661180 | 0.89 | HPGD (0.41) | PTPN1PDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL10657848 | 0.82 | PDE3B (0.47) | PDE3BPDE3AP2RY12ALDH1A1MAPT | |
| SCHEMBL10657191 | 0.82 | HPGD (0.44) | PTPN1PDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL10657188 | 0.82 | HPGD (0.44) | PTPN1PDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL10656100 | 0.81 | HPGD (0.45) | PTPN1PDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL10656094 | 0.81 | HPGD (0.45) | PTPN1PDE3BPDE3AP2RY12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775674-A | CARDIOTONIC AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-10-04 | — | — | US | disclosed |