Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KLK7 | P49862 | 2/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10659094 | 1.00 | MAPT (0.62) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL11021538 | 0.92 | MAPT (0.60) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL10661677 | 0.92 | MAPT (0.60) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL1022850 | 0.86 | MAPT (0.66) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL29458730 | 0.85 | MAPT (0.63) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL16789691 | 0.83 | MAPT (0.63) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL1024150 | 0.83 | MAPT (0.62) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL16279057 | 0.83 | MAPT (0.62) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL29458707 | 0.82 | MAPT (0.62) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL24845246 | 0.82 | MAPT (0.70) | MAPTKLK7KLK5ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746649-A | Diamino acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1988-05-24 | — | — | US | disclosed |
| EP-0161588-A2 | Diamino acid derivatives | MERCK PATENT GmbH (DE) | 1985-11-21 | — | — | EP | disclosed |