Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 17/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656400 | 0.91 | ACE (0.58) | ACEACE2TSHR | |
| SCHEMBL10679400 | 0.87 | ACE (0.66) | ACEACE2TSHR | |
| SCHEMBL10655570 | 0.85 | ACE (0.76) | ACEACE2 | |
| SCHEMBL10656703 | 0.85 | ACE (0.76) | ACEACE2 | |
| SCHEMBL10663756 | 0.84 | ACE (0.54) | ACEACE2 | |
| SCHEMBL10661188 | 0.82 | ACE (0.70) | ACEACE2TSHR | |
| SCHEMBL10656439 | 0.80 | ACE (0.72) | ACEACE2 | |
| SCHEMBL11435575 | 0.79 | ACE (0.71) | ACEACE2TSHR | |
| SCHEMBL29749309 | 0.79 | ACE (0.71) | ACEACE2TSHR | |
| SCHEMBL3472327 | 0.79 | ACE (0.71) | ACEACE2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736066-A | Intermediate for substituted peptide compounds | E. R. SQUIBB & SONS, INC. (US) | 1988-04-05 | — | — | US | disclosed |
| US-4535176-A | HYPOTENSIVE AGENTS, ANALGESICS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4470973-A | HYPOTENSIVE AGENTS, ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1984-09-11 | — | — | US | disclosed |