Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662817 | 0.89 | ACE (0.46) | ACELMNASMN1; SMN2FKBP1APREP | |
| SCHEMBL10657952 | 0.89 | ACE (0.54) | ACELMNASMN1; SMN2PREPLTA4H | |
| SCHEMBL10655550 | 0.89 | ACE (0.52) | ACELMNASMN1; SMN2PREPLTA4H | |
| SCHEMBL10658161 | 0.89 | ACE (0.52) | ACELMNASMN1; SMN2PREPLTA4H | |
| SCHEMBL10662821 | 0.89 | ACE (0.45) | ACELMNASMN1; SMN2FKBP1APREP | |
| SCHEMBL10785790 | 0.85 | ACE (0.64) | ACECMA1 | |
| SCHEMBL10785793 | 0.85 | ACE (0.64) | ACECMA1 | |
| SCHEMBL28551091 | 0.83 | ACE (0.54) | ACELMNACMA1SMN1; SMN2LTA4H | |
| SCHEMBL10660541 | 0.81 | ACE (0.54) | ACELMNASMN1; SMN2PREPLTA4H | |
| SCHEMBL7368526 | 0.81 | ACE (0.51) | ACELMNACMA1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736066-A | Intermediate for substituted peptide compounds | E. R. SQUIBB & SONS, INC. (US) | 1988-04-05 | — | — | US | disclosed |
| US-4535176-A | HYPOTENSIVE AGENTS, ANALGESICS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4470973-A | HYPOTENSIVE AGENTS, ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1984-09-11 | — | — | US | disclosed |