Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | PPOX | P50336 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10791384 | 0.90 | TDP1 (0.63) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10678017 | 0.89 | TDP1 (0.62) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10675557 | 0.88 | TDP1 (0.61) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen-Methyl SCHEMBL39092 | 0.87 | MEN1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10661152 | 0.87 | TDP1 (0.60) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen-Methyl SCHEMBL30749491 | 0.87 | MEN1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen-Methyl SCHEMBL31614705 | 0.87 | MEN1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10784991 | 0.85 | TDP1 (0.58) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10773049 | 0.85 | TDP1 (0.53) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11023426 | 0.85 | TDP1 (0.58) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780128-A | Herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-25 | — | — | US | disclosed |
| US-4738711-A | POST- AND PREEMERGENCE HERBICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-04-19 | — | — | US | disclosed |
| US-4465508-A | Diphenyl ether herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-14 | — | — | US | disclosed |
| EP-0023392-B1 | DIPHENYL ETHER COMPOUNDS, AND HERBICIDAL COMPOSITIONS AND PROCESSES UTILISING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-06 | — | — | EP | disclosed |
| EP-0023392-A2 | Diphenyl ether compounds, and herbicidal compositions and processes utilising them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-02-04 | — | — | EP | disclosed |