Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10343497 | 0.80 | TSHR (0.54) | TSHRNR3C1PGRNR3C2AR | |
| SCHEMBL5406221 | 0.78 | TSHR (0.66) | TSHRNR3C1TRPM8MAPK1CNR2 | |
| SCHEMBL3403622 | 0.77 | TSHR (0.59) | TSHRNR3C1TRPM8MAPK1PGR | |
| SCHEMBL6854532 | 0.77 | CNR2 (0.48) | TSHRNR3C1TRPM8CNR2CNR1 | |
| Sulfuric Acid SCHEMBL8957948 | 0.76 | TSHR (0.79) | TSHRNR3C1MAPK1CNR2CNR1 | |
| SCHEMBL11734487 | 0.75 | TSHR (0.56) | TSHRNR3C1TRPM8MAPK1PGR | |
| SCHEMBL13280135 | 0.74 | TSHR (0.51) | TSHRNR3C1MAPK1PGRNR3C2 | |
| SCHEMBL10657988 | 0.74 | TSHR (0.51) | TSHRMAPK1CNR2CNR1 | |
| SCHEMBL9717458 | 0.74 | TSHR (0.64) | TSHRCNR2CNR1 | |
| Sulfuric Acid SCHEMBL11038237 | 0.73 | TSHR (0.58) | TSHRNR3C1CNR2CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734490-A | TEXTILE DYEING AND PRINTING | CIBA-GEIGY CORPORATION (US) | 1988-03-29 | — | — | US | disclosed |