Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | PDE4A | P27815 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566515 | 0.91 | CYP3A4 (0.51) | CYP3A4SMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL10566510 | 0.91 | CYP3A4 (0.51) | CYP3A4SMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL10571122 | 0.84 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL10571125 | 0.84 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL10656338 | 0.83 | MAPT (0.50) | CYP3A4SMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL10564768 | 0.83 | MAPT (0.50) | CYP3A4SMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL10364563 | 0.79 | MAPT (0.56) | CYP3A4SMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL10364565 | 0.79 | MAPT (0.56) | CYP3A4SMN1; SMN2TSHRMAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL10568449 | 0.78 | TSHR (0.57) | CYP3A4SMN1; SMN2TSHRMAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL10568441 | 0.78 | TSHR (0.57) | CYP3A4SMN1; SMN2TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123402-B1 | PYRIMIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |