Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10658585 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL10658592 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL10655091 | 0.93 | KDM4E (0.59) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL10655095 | 0.93 | KDM4E (0.59) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL10655107 | 0.93 | KDM4E (0.59) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL10658808 | 0.93 | KDM4E (0.58) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL10658815 | 0.93 | KDM4E (0.58) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL10658825 | 0.93 | KDM4E (0.58) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL10658818 | 0.93 | KDM4E (0.60) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL10658827 | 0.93 | KDM4E (0.60) | KDM4EALDH1A1LMNATOP2BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762845-A | BACTERICIDES | ABBOTT LABORATORIES (US) | 1988-08-09 | — | — | US | disclosed |