Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TOP1 | P11387 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660043 | 1.00 | HPGD (0.60) | HPGDLMNAPOLBTAAR1DRD3 | |
| SCHEMBL10657143 | 0.94 | DRD3 (0.58) | HPGDLMNAPOLBTAAR1DRD3 | |
| SCHEMBL10657129 | 0.94 | DRD3 (0.58) | HPGDLMNAPOLBTAAR1DRD3 | |
| SCHEMBL10657125 | 0.94 | DRD3 (0.58) | HPGDLMNAPOLBTAAR1DRD3 | |
| SCHEMBL10657240 | 0.94 | DRD3 (0.57) | HPGDLMNAPOLBTAAR1DRD3 | |
| SCHEMBL10657231 | 0.94 | DRD3 (0.57) | HPGDLMNAPOLBTAAR1DRD3 | |
| SCHEMBL10657249 | 0.94 | DRD3 (0.57) | HPGDLMNAPOLBTAAR1DRD3 | |
| SCHEMBL10660047 | 0.90 | DRD3 (0.53) | HPGDLMNAPOLBTAAR1DRD3 | |
| SCHEMBL8132965 | 0.86 | DRD3 (0.61) | HPGDLMNADRD3KDM4EHTT | |
| SCHEMBL10658827 | 0.86 | KDM4E (0.60) | HPGDLMNAKDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762845-A | BACTERICIDES | ABBOTT LABORATORIES (US) | 1988-08-09 | — | — | US | disclosed |