Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10659646 | 1.00 | ACE (0.44) | ACEACE2 | |
| SCHEMBL10656816 | 0.85 | ACE (0.49) | ACEACE2 | |
| SCHEMBL10659374 | 0.82 | ACE (0.49) | ACEACE2 | |
| SCHEMBL10657986 | 0.82 | ACE (0.53) | ACEACE2 | |
| SCHEMBL10655287 | 0.81 | ACE (0.67) | ACEACE2 | |
| SCHEMBL7365526 | 0.81 | ACE (0.66) | ACEACE2 | |
| SCHEMBL7365528 | 0.81 | ACE (0.66) | ACEACE2 | |
| SCHEMBL10980638 | 0.75 | ACE (0.52) | ACEACE2 | |
| SCHEMBL10657977 | 0.75 | ACE (0.64) | ACEACE2 | |
| SCHEMBL10657322 | 0.74 | ACE (0.54) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736066-A | Intermediate for substituted peptide compounds | E. R. SQUIBB & SONS, INC. (US) | 1988-04-05 | — | — | US | disclosed |