Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.46 |
| ▸ | PPARA | Q07869 | 16/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.45 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10663764 | 0.91 | SMN1; SMN2 (0.45) | PPARGPPARAALDH2CTRC | |
| SCHEMBL10656236 | 0.90 | ALDH2 (0.46) | PPARGPPARAALDH2 | |
| SCHEMBL3378337 | 0.85 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL10658226 | 0.83 | AR (0.53) | ALDH2 | |
| SCHEMBL10660557 | 0.80 | ALDH2 (0.50) | PPARGALDH2 | |
| SCHEMBL10658222 | 0.78 | ESR1 (0.41) | PPARGPPARA | |
| SCHEMBL10663175 | 0.78 | MAP4K4 (0.50) | PPARGPPARAALDH2 | |
| SCHEMBL10875312 | 0.77 | PPARA (0.66) | PPARGPPARA | |
| SCHEMBL10660550 | 0.77 | PPARA (0.43) | PPARGPPARA | |
| SCHEMBL10662939 | 0.76 | PPARA (0.55) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | claimed |
| US-4728662-A | DIURETICS, URICOSURICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-03-01 | — | — | US | disclosed |
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | disclosed |