Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233304 | 0.78 | ELANE (1.00) | ELANETP53SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2077025 | 0.75 | ELANE (0.78) | ELANETP53SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL10656661 | 0.74 | ELANE (0.76) | ELANETP53SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL10659186 | 0.74 | ELANE (0.65) | ELANETP53SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2076871 | 0.73 | ELANE (0.74) | ELANETP53SMN1; SMN2MAPT | |
| SCHEMBL10655020 | 0.73 | ELANE (0.56) | ELANE | |
| SCHEMBL2079239 | 0.72 | ELANE (0.68) | ELANETP53SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL12844728 | 0.72 | ELANE (0.72) | ELANETP53SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2078449 | 0.72 | ELANE (0.72) | ELANETP53SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13039558 | 0.72 | ELANE (0.72) | ELANETP53SMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |
| US-4665070-A | SERINE PROTEINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1987-05-12 | — | — | US | disclosed |