Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.56 |
| ▸ | PPARD | Q03181 | 17/20 | 0.56 |
| ▸ | PPARA | Q07869 | 17/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10659796 | 0.91 | PPARD (0.48) | PPARGPPARDPPARAPTGDR2FFAR4 | |
| SCHEMBL10661241 | 0.89 | PPARG (0.46) | PPARGPPARDPPARAPTGDR2FFAR4 | |
| SCHEMBL10660124 | 0.89 | PPARG (0.48) | PPARGPPARDPPARAPTGDR2 | |
| SCHEMBL10656305 | 0.89 | PPARG (0.46) | PPARGPPARDPPARAPTGDR2FFAR4 | |
| SCHEMBL10659746 | 0.88 | PPARD (0.48) | PPARGPPARDPPARAPTGDR2FFAR4 | |
| SCHEMBL10655770 | 0.88 | PTGER2 (0.50) | PPARGPPARDPPARAPTGDR2 | |
| SCHEMBL10662895 | 0.87 | PPARD (0.52) | PPARGPPARDPPARAPTGDR2 | |
| SCHEMBL10730658 | 0.87 | FFAR4 (0.47) | PPARGPPARDPPARAPTGDR2FFAR4 | |
| SCHEMBL10661038 | 0.86 | PPARD (0.46) | PPARGPPARDPPARA | |
| SCHEMBL10660472 | 0.86 | PPARG (0.43) | PPARGPPARDPPARAPTGDR2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | claimed |
| US-4728662-A | DIURETICS, URICOSURICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-03-01 | — | — | US | disclosed |
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | disclosed |