Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11666481 | 0.92 | DHODH (0.53) | DHODHCNR1HDAC3HDAC1HDAC2 | |
| SCHEMBL11666477 | 0.92 | DHODH (0.53) | DHODHCNR1HDAC3HDAC1HDAC2 | |
| SCHEMBL11659158 | 0.81 | DHODH (0.54) | DHODHCNR1HDAC3HDAC1HDAC2 | |
| SCHEMBL11659163 | 0.81 | DHODH (0.54) | DHODHCNR1HDAC3HDAC1HDAC2 | |
| SCHEMBL30824201 | 0.79 | MDM2 (0.47) | DHODHPOLBSTAT3SMN1; SMN2TAAR1 | |
| SCHEMBL11194081 | 0.78 | CNR1 (0.50) | DHODHCNR1HDAC3HDAC1HDAC2 | |
| SCHEMBL11656612 | 0.78 | DHODH (0.72) | DHODHCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11652333 | 0.78 | DHODH (0.50) | DHODHCNR1HDAC3HDAC1HDAC2 | |
| SCHEMBL11652335 | 0.78 | DHODH (0.50) | DHODHCNR1HDAC3HDAC1HDAC2 | |
| SCHEMBL11656609 | 0.78 | DHODH (0.72) | DHODHCYP17A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554352-A | Preparation of 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid | ETHYL CORPORATION (US) | 1985-11-19 | — | — | US | claimed |
| US-4552963-A | Preparation of 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid | ETHYL CORPORATION (US) | 1985-11-12 | — | — | US | claimed |
| US-4550167-A | Preparation of 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinoline carboxylic acid | ETHYL CORPORATION (US) | 1985-10-29 | — | — | US | claimed |
| US-4533735-A | Process for preparing antibacterial compounds | ETHYL CORPORATION (US) | 1985-08-06 | — | — | US | claimed |
| US-4532326-A | Decarboxylation process for preparing 4-(3-aminophenyl)pyridines | ETHYL CORPORATION (US) | 1985-07-30 | — | — | US | claimed |
| US-4727148-A | Certain aromatization process for preparing 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinoline carboxylic acid | ETHYL CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4649202-A | Brominative aromatization of 4-cyclohexenylpyridines | ETHYL CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4604467-A | Certain 4-(3,4-dibromocyclohexyl)pyridines | ETHYL CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |
| US-4554352-A | Preparation of 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid | ETHYL CORPORATION (US) | 1985-11-19 | — | — | US | disclosed |
| US-4552963-A | Preparation of 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid | ETHYL CORPORATION (US) | 1985-11-12 | — | — | US | disclosed |
| US-4552964-A | 4-(1-Chlorocyclohex-3-enyl)pyridines and preparation of 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid | ETHYL CORPORATION (US) | 1985-11-12 | — | — | US | disclosed |
| US-4550167-A | Preparation of 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinoline carboxylic acid | ETHYL CORPORATION (US) | 1985-10-29 | — | — | US | disclosed |
| US-4533735-A | Process for preparing antibacterial compounds | ETHYL CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| US-4532326-A | Decarboxylation process for preparing 4-(3-aminophenyl)pyridines | ETHYL CORPORATION (US) | 1985-07-30 | — | — | US | disclosed |