Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10667849 | 0.80 | HPGD (0.54) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL10670783 | 0.74 | HPGD (0.48) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL10669211 | 0.74 | HPGD (0.47) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27348687 | 0.72 | CA1 (0.42) | ALDH1A1TSHRPDK2PDK4 | |
| SCHEMBL4155308 | 0.70 | HSP90AA1 (0.61) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL3917299 | 0.69 | HPGD (0.83) | HPGDALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL4491431 | 0.69 | HPGD (0.83) | HPGDALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL4050706 | 0.69 | HPGD (0.83) | HPGDALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL4159603 | 0.68 | HSP90AA1 (0.63) | ALDH1A1NPC1RAB9APOLBTSHR | |
| SCHEMBL4496125 | 0.68 | HPGD (0.61) | HPGDALDH1A1NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788187-A | ANTISECRETORY AND ANTIULCEROGENIC AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| US-4743600-A | ANTIULCER, ANTISECRETORY | RORER PHARMACEUTICAL CORPORATION (US) | 1988-05-10 | — | — | US | disclosed |
| US-4639442-A | ANTIULCER | WILLIAM H. RORER, INC. (US) | 1987-01-27 | — | — | US | disclosed |
| EP-0182815-A4 | BENZOCYCLOBUTENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES. | RORER INTERNAT OVERSEAS INC (US) | 1986-10-14 | — | — | EP | disclosed |
| EP-0182815-A1 | BENZOCYCLOBUTENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1986-06-04 | — | — | EP | disclosed |
| WO-1985005032-A1 | BENZOCYCLOBUTENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1985-11-21 | — | — | WO | disclosed |