Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666220 | 0.86 | TSHR (0.60) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10876854 | 0.80 | MAPT (0.74) | MAPTTP53NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL2886423 | 0.79 | MAPT (1.00) | MAPTTP53NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL10667693 | 0.78 | MAPT (0.70) | MAPTTP53NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL10668699 | 0.76 | MAPT (0.67) | MAPTTP53NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL10664826 | 0.73 | MAPK1 (0.45) | MAPTTP53NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL10685547 | 0.70 | MAPT (0.63) | MAPTTP53NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL2882728 | 0.69 | HRH3 (0.65) | TSHRMAPK1HSD17B10 | |
| SCHEMBL13996077 | 0.67 | NPSR1 (0.66) | MAPTTP53NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL496814 | 0.67 | MAPT (0.76) | MAPTTP53NPSR1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788186-A | ANXIOLYTIC AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1988-11-29 | — | — | US | disclosed |
| EP-0085840-B1 | NEW 6-SUBSTITUTED-S-TRIAZOLO(3,4-A)PHTHALAZINE DERIVATIVES | GRUPPO LEPETIT S.P.A. (IT) | 1986-10-01 | — | — | EP | disclosed |
| EP-0085840-A1 | New 6-substituted-s-triazolo(3,4-a)phthalazine derivatives | GRUPPO LEPETIT S.P.A. (IT) | 1983-08-17 | — | — | EP | disclosed |