Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | PPOX | P50336 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10667134 | 0.87 | TDP1 (0.70) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10789111 | 0.86 | TDP1 (0.73) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10667783 | 0.82 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL2730973 | 0.81 | TDP1 (0.76) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10789827 | 0.81 | TDP1 (0.76) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL38816 | 0.80 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL8541647 | 0.80 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL30862569 | 0.80 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Potassium Ion SCHEMBL11543008 | 0.80 | TDP1 (0.74) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10789623 | 0.80 | TDP1 (0.74) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4744818-A | Herbicidal N-halo-5(substituted-phenoxy or -pyridyloxy)-2-substituted benzoic acid sulfonamides and sulfamates | RHONE-POULENC AGROCHIMIE (FR) | 1988-05-17 | — | — | US | disclosed |