Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668576 | 1.00 | CA1 (0.52) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10669720 | 0.98 | CA1 (0.50) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10667153 | 0.98 | CA1 (0.50) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10667149 | 0.98 | CA1 (0.50) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10671344 | 0.98 | CA1 (0.50) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10671232 | 0.98 | CA1 (0.50) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10671238 | 0.98 | CA1 (0.50) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10669807 | 0.98 | CA1 (0.50) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10671339 | 0.98 | CA1 (0.50) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10669724 | 0.98 | CA1 (0.50) | CA1ACE2FFAR1FFAR4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4774342-A | ANTITUMOR AGENTS | SUNTORY LIMITED (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0108645-B1 | NOVEL AILANTHONE DERIVATIVE | SUNTORY LIMITED (JP) | 1987-05-13 | — | — | EP | disclosed |
| EP-0108645-A2 | Novel ailanthone derivative | SUNTORY LIMITED (JP) | 1984-05-16 | — | — | EP | disclosed |