Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10667435 | 1.00 | MEN1 (0.79) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL10422665 | 0.89 | MEN1 (0.77) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL10422505 | 0.89 | MEN1 (0.77) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL10424272 | 0.89 | MEN1 (0.77) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL992112 | 0.89 | MEN1 (1.00) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL11561346 | 0.89 | MEN1 (1.00) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL11558887 | 0.89 | MEN1 (1.00) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL10422671 | 0.89 | MEN1 (0.77) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL9060429 | 0.89 | MEN1 (1.00) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL10423929 | 0.89 | MEN1 (0.77) | MEN1KMT2ATDP1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738984-A | SUBSTITUTED 5-OXY-2-FURYL KETONE | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-04-19 | — | — | US | disclosed |
| US-4602099-A | Antirhinovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-07-22 | — | — | US | disclosed |