Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830460 | 0.83 | CNR1 (0.44) | CNR1GPR55PKMALDH1A1NPC1 | |
| SCHEMBL9831187 | 0.82 | CNR1 (0.43) | CNR1GPR55PKMALDH1A1NPC1 | |
| SCHEMBL9828953 | 0.81 | CNR1 (0.42) | CNR1GPR55PKMALDH1A1NPC1 | |
| SCHEMBL9831057 | 0.80 | CNR1 (0.44) | CNR1GPR55PKMALDH1A1NPC1 | |
| SCHEMBL9829469 | 0.80 | CNR1 (0.41) | CNR1GPR55PKMALDH1A1NPC1 | |
| SCHEMBL9829132 | 0.79 | CNR1 (0.40) | CNR1GPR55PKMALDH1A1NPC1 | |
| SCHEMBL9831468 | 0.77 | CNR1 (0.41) | CNR1GPR55PKMALDH1A1NPC1 | |
| SCHEMBL9831101 | 0.76 | CNR1 (0.38) | CNR1GPR55PKMALDH1A1NPC1 | |
| SCHEMBL10675808 | 0.76 | BACE1 (0.38) | ALDH1A1NPC1TP53CYP1A2CYP2C19 | |
| SCHEMBL10673375 | 0.75 | BACE1 (0.38) | ALDH1A1CYP2C19GAAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |