Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669461 | 1.00 | KDM4E (0.41) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10667408 | 0.86 | KDM4E (0.40) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10667400 | 0.86 | KDM4E (0.40) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10665796 | 0.85 | CDC25A (0.42) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10665789 | 0.85 | CDC25A (0.42) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10661496 | 0.84 | CDC25A (0.44) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10662819 | 0.84 | CDC25A (0.44) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10666033 | 0.84 | CDC25A (0.44) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10664577 | 0.84 | CDC25A (0.44) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10661502 | 0.84 | CDC25A (0.44) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | disclosed |