Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669795 | 1.00 | MAPT (0.44) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10664712 | 0.92 | MAPT (0.45) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10669913 | 0.92 | MAPT (0.45) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10669908 | 0.92 | MAPT (0.45) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10664713 | 0.92 | MAPT (0.45) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10890221 | 0.90 | MAPT (0.44) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10890216 | 0.90 | MAPT (0.44) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10671161 | 0.89 | NR1I2 (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9482978 | 0.89 | TDP1 (0.49) | MAPTALDH1A1HPGDKCNH2NR1I2 | |
| SCHEMBL9482974 | 0.89 | TDP1 (0.49) | MAPTALDH1A1HPGDKCNH2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4751295-A | 7-(2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-OXYIMINOACETAMIDO)-3-(3 -(QUATERNARY AMMONIO)-1-PROPEN-1-YL)-3-CEPHEM-4-CARBOXYLATES | BRISTOL-MYERS COMPANY (US) | 1988-06-14 | — | — | US | disclosed |