Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.60 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878070 | 0.90 | HSD17B10 (0.73) | HSD17B10DRD3KDM4EALDH1A1HPGD | |
| SCHEMBL29548937 | 0.86 | HSD17B10 (0.78) | HSD17B10DRD3KDM4EALDH1A1HPGD | |
| SCHEMBL27397656 | 0.86 | HSD17B10 (0.78) | HSD17B10DRD3KDM4EALDH1A1HPGD | |
| SCHEMBL21074647 | 0.86 | HSD17B10 (0.69) | HSD17B10DRD3KDM4EALDH1A1HPGD | |
| SCHEMBL10678719 | 0.86 | HSD17B10 (0.72) | HSD17B10DRD3KDM4EALDH1A1HPGD | |
| SCHEMBL10677674 | 0.85 | HSD17B10 (0.74) | HSD17B10DRD3KDM4EALDH1A1HPGD | |
| 4-N-Acetyl-1-Piperazinyl-Norfloxacin SCHEMBL11027379 | 0.85 | HSD17B10 (0.83) | HSD17B10DRD3KDM4EALDH1A1HPGD | |
| 4-N-Acetyl-1-Piperazinyl-Norfloxacin SCHEMBL30570718 | 0.85 | HSD17B10 (0.83) | HSD17B10DRD3KDM4EALDH1A1HPGD | |
| SCHEMBL30306133 | 0.84 | HSD17B10 (0.75) | HSD17B10DRD3KDM4EALDH1A1HPGD | |
| SCHEMBL4768364 | 0.84 | HSD17B10 (0.75) | HSD17B10DRD3KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760057-A | (Acyloxyalkoxy)carbonyl derivatives as bioreversible prodrug moieties for primary and secondary amine functions in drugs | MERCK & CO., INC. (US) | 1988-07-26 | — | — | US | claimed |
| EP-0130119-A2 | (Acyloxyalkoxy) carbonyl derivatives as bioreversible prodrug moieties for primary and secondary amine functions in drugs, their preparation and pharmaceutical compositions containing said derivatives | MERCK & CO. INC. (US) | 1985-01-02 | — | — | EP | disclosed |