Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679109 | 0.92 | MAPT (0.67) | MAPTALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL10676817 | 0.90 | MAPT (0.60) | MAPTALDH1A1LMNASMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL10673037 | 0.88 | MAPK1 (0.70) | MAPTALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL10681575 | 0.87 | MAPT (0.57) | MAPTALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL10673931 | 0.87 | GAA (0.71) | MAPTALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL10673454 | 0.85 | MAPT (0.66) | MAPTALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL10681731 | 0.84 | PDE5A (0.62) | MAPTALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL10677651 | 0.84 | SMN1; SMN2 (0.55) | MAPTALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL10678126 | 0.84 | MEN1 (0.70) | MAPTALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL10673494 | 0.83 | MAPK1 (0.53) | MAPTALDH1A1LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788188-A | ANTICONVULSANTS, SEDATIVES, ANXIOLYTIC AGENTS | SANOFI (S.A.) (FR) | 1988-11-29 | — | — | US | disclosed |