Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 13/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10670567 | 1.00 | AVPR1A (0.55) | AVPR1ATP53ALDH1A1POLBMAPT | |
| SCHEMBL10671745 | 0.89 | AVPR1A (0.56) | AVPR1ATP53ALDH1A1POLBMAPT | |
| SCHEMBL10675501 | 0.89 | AVPR1A (0.56) | AVPR1ATP53ALDH1A1POLBMAPT | |
| SCHEMBL11016392 | 0.89 | AVPR1A (0.56) | AVPR1ATP53ALDH1A1POLBMAPT | |
| SCHEMBL10677562 | 0.89 | AVPR1A (0.56) | AVPR1ATP53ALDH1A1POLBMAPT | |
| SCHEMBL10680024 | 0.89 | AVPR1A (0.56) | AVPR1ATP53ALDH1A1POLBMAPT | |
| SCHEMBL10674393 | 0.85 | AVPR1A (0.69) | AVPR1ATP53ALDH1A1POLBMAPT | |
| SCHEMBL10673134 | 0.85 | AVPR1A (0.69) | AVPR1ATP53ALDH1A1POLBMAPT | |
| SCHEMBL10676270 | 0.83 | AVPR1A (0.51) | AVPR1ATP53POLBMAPTLMNA | |
| SCHEMBL10672790 | 0.83 | AVPR1A (0.51) | AVPR1ATP53POLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4751299-A | Optically active β-lactams and method of their production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0144840-A2 | Optically active beta-lactams and method of their production | Takeda Chemical Industries, Ltd. (JP) | 1985-06-19 | — | — | EP | disclosed |