Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680846 | 1.00 | AVPR1A (0.59) | AVPR1AALDH1A1GAANPC1RAB9A | |
| SCHEMBL10674647 | 0.88 | AVPR1A (0.55) | AVPR1APOLBMEN1KMT2A | |
| SCHEMBL10672540 | 0.88 | AVPR1A (0.55) | AVPR1APOLBMEN1KMT2A | |
| SCHEMBL10674633 | 0.88 | AVPR1A (0.55) | AVPR1APOLBMEN1KMT2A | |
| SCHEMBL10672548 | 0.88 | AVPR1A (0.55) | AVPR1APOLBMEN1KMT2A | |
| SCHEMBL10671321 | 0.88 | AVPR1A (0.55) | AVPR1APOLBMEN1KMT2A | |
| SCHEMBL10671312 | 0.88 | AVPR1A (0.55) | AVPR1APOLBMEN1KMT2A | |
| SCHEMBL10673865 | 0.87 | AVPR1A (0.54) | AVPR1AALDH1A1MEN1KMT2A | |
| SCHEMBL10671917 | 0.87 | AVPR1A (0.53) | AVPR1AMEN1KMT2A | |
| SCHEMBL10671912 | 0.87 | AVPR1A (0.53) | AVPR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4751299-A | Optically active β-lactams and method of their production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-06-14 | — | — | US | claimed |