Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500816 | 0.85 | KDM4E (0.61) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10383416 | 0.85 | MAPT (0.54) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL30843076 | 0.85 | KDM4E (0.61) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10678788 | 0.85 | KMT2A (0.56) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL584002 | 0.83 | KDM4E (0.56) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10330759 | 0.83 | KDM4E (0.59) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10741852 | 0.83 | KDM4E (0.59) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| Fluoride SCHEMBL6756478 | 0.83 | KDM4E (0.59) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10457822 | 0.83 | KDM4E (0.56) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL13581396 | 0.82 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719302-A | 1,7-phenanthrolines and their use as antifungal agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-12 | — | — | US | claimed |
| US-4719302-A | 1,7-phenanthrolines and their use as antifungal agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |