Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677007 | 1.00 | HTR2C (0.54) | HTR2CSLC6A2SLC6A4TACR1KDM1A | |
| Hydrochloric Acid SCHEMBL6439127 | 0.85 | HTR2C (0.61) | HTR2CTACR1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL6439125 | 0.85 | HTR2C (0.61) | HTR2CTACR1KDM1AMAOAMAOB | |
| SCHEMBL6438889 | 0.85 | KDM1A (0.54) | SLC6A2SLC6A4KDM1AMAOAMAOB | |
| SCHEMBL10682790 | 0.85 | KDM1A (0.54) | SLC6A2SLC6A4KDM1AMAOAMAOB | |
| SCHEMBL6438894 | 0.85 | KDM1A (0.54) | SLC6A2SLC6A4KDM1AMAOAMAOB | |
| SCHEMBL10682798 | 0.85 | KDM1A (0.54) | SLC6A2SLC6A4KDM1AMAOAMAOB | |
| SCHEMBL11103589 | 0.80 | SLC6A2 (0.51) | HTR2CSLC6A2SLC6A4TACR1KDM1A | |
| SCHEMBL11103561 | 0.80 | SLC6A2 (0.51) | HTR2CSLC6A2SLC6A4TACR1KDM1A | |
| SCHEMBL11103529 | 0.80 | SLC6A2 (0.51) | HTR2CSLC6A2SLC6A4TACR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273199-A2 | Uses of 3,4-diphenyl piperidine derivatives or medicines, 3,4-diphenyl piperidine derivatives, and process for their preparation | LABORATOIRES HOECHST S.A. (FR) | 1988-07-06 | — | — | EP | claimed |
| EP-0273199-A2 | Uses of 3,4-diphenyl piperidine derivatives or medicines, 3,4-diphenyl piperidine derivatives, and process for their preparation | LABORATOIRES HOECHST S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |