Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | EDNRA | P25101 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17268647 | 0.88 | HDAC4 (0.63) | F2PRSS1PRSS2PRSS3HDAC4 | |
| Dansylglycine SCHEMBL386439 | 0.88 | HDAC4 (0.60) | F2PRSS1PRSS2PRSS3HDAC4 | |
| Dansylglycine SCHEMBL31496395 | 0.88 | HDAC4 (0.60) | F2PRSS1PRSS2PRSS3HDAC4 | |
| SCHEMBL17268847 | 0.85 | HDAC4 (0.61) | F2PRSS1PRSS2PRSS3HDAC4 | |
| SCHEMBL8016351 | 0.84 | HDAC4 (0.79) | F2PRSS1PRSS2PRSS3HDAC4 | |
| SCHEMBL18972443 | 0.83 | HDAC4 (0.58) | F2PRSS1PRSS2PRSS3HDAC4 | |
| SCHEMBL15586444 | 0.82 | HDAC4 (0.55) | F2PRSS1PRSS2PRSS3HDAC4 | |
| SCHEMBL9751653 | 0.82 | HDAC4 (0.57) | F2PRSS1PRSS2PRSS3HDAC4 | |
| Dansylglycine SCHEMBL4273131 | 0.82 | HDAC4 (0.52) | F2PRSS1PRSS2PRSS3HDAC4 | |
| SCHEMBL11128861 | 0.81 | EDNRA (0.63) | F2PRSS1PRSS2PRSS3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166900-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | UGISENSE AG (DE) | 2017-06-15 | — | — | US | disclosed |
| US-4743611-A | TREATMENT OF DIABETIC COMPLICATIONS | AMERICAN HOME PRODUCTS CORP. (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0251784-A2 | Naphthalenylsulfonylimidazolidinediones and their thioxo analogs | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166900-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | DTYMK, POLM, PNKP | F2 3623/4885PRSS1 2409/4885PRSS2 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.